PRODUCT CONTACT:

Shayz Ikram
Product Specialist
01372 378822
SCREEN Cell3iMager 2D and 3D cell culture scanners

SCREEN Cell3iMager

Bright field scanners designed to simplify and accelerate quantitative and qualitative measurement of 3D spheroids

Cell3iMager systems developed by SCREEN are 2D and 3D cell culture scanners are able to perform high-speed measurement and analysis of the multiplication and morphological changes in cells without using any test reagent.

The devices use proprietary image processing technologies that allow faster image capture, measurement and data analysis, and are compatible with all major 2D and 3D cell culture platforms.

Contact: Shayz Ikram
Product Specialist

01372 378822
shayz@qd-uki.co.uk

Models

Cell3iMager Neo from SCREEN

SCREEN Cell3iMagers are bright field scanners designed specifically to simplify and accelerate quantitative and qualitative measurement of 3D spheroids. This unique LED-based imaging system allows the user to identify and measure single or multiple spheroids per well in a microplate rapidly and automatically. The companion 3D optimized analysis software allows faster image capture, measurement and data analysis, and is compatible with all major 3D cell culture platforms. To fit varying budgets and throughput needs, the imager is available in two models: the single-plate Cell3iMager Neo (cc-3000) or the four-plate Cell3iMager (cc-5000).

Features

LED-based imaging system

Rapid scan time up to 30 × 384-well plates/hour

Preset plate definitions for all major cell culture platforms

Comprehensive 2D and 3D image analysis software


Applications

Phenotypic drug discovery

Drug sensitivity testing

Co-culture: loss of spheroid volume

Combinatorial drug testing

Drug-target discovery and validation

Quality control

Cell3iMagers Duos

Cell3iMagers Duos is a benchtop imager capable of high-throughput, whole-well imaging at high-resolution, and provides both bright-field and fluorescence imaging options. It can be used as a valuable tool in several drug discovery and development applications as well as toxicology testing to select therapeutic targets and treatment strategies before costly and tedious testing in animal models. Cell3iMagers Duos facilitate uniform, whole-well imaging of each and every cell in a well, including well periphery, at high-resolutions. Duos proprietary lens captures images at two different resolutions, 0.8 µm & 4.0 µm, thus enable qualitative and quantitative measurement of single cells and colonies grown in 2D culture as well as growth and morphological changes of spheroids/organoids grown in 3D culture. Duos automatic cell morphological classification (ACMC) feature allows ‘intelligent’ automatic classification of live and dead spheroids/cells, using logic derived from a user-defined reference set of respective objects.

Features

2D and 3D cellular high-resolution imaging

Uniform analysis of whole well without any edge effects

Compatible with both adherent and suspension cultures

Multi-channel fluorescence mode available

Powerful intuitive image analysis software

 

Applications

Phenotypic drug discovery

Drug sensitivity testing

Co-culture: loss of spheroid volume

Combinatorial drug testing

Drug-target discovery and validation

Quality control

 

Cell3iMager Estier

SCREEN's Cell3iMager Estier employs the optical coherence tomography (OCT) technology used in the opthalmology field for the examination of retinas.  It does not require any special preparations and great simplifies the safe, non-invasive capture of 3D images of tissue samples and organoids created from iPS cells, ES cells and more.

Features

Non-invasive deep tissue imaging:  Enables non-invasive detection of internal cavities and gaps in tissues up to 1mm thick

Sample differentation: Allows differentiation of samples by detecting the image contract originating from variances in the sample's physical density (refractive index)

True 3D imaging:  A 300µm 3D image can be acquired in 1 minute. High resolution (3µm) and low resolution (10µm) imaging options with accurate focus options

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